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Zolpidem

A sleeping pill used for short-term treatment of severe insomnia.

Clinical information

Common uses

  • short-term treatment of severe insomnia

Common side effects

  • bitter or metallic taste, or dry mouth
  • feeling sleepy or tired the next day
  • headaches
  • feeling dizzy
  • feeling or being sick

Cautions

  • short-term use only (up to 4 weeks) — your body can become dependent
  • do not drink alcohol while taking it
  • do not drive or use machinery if sleepy the next day
  • sleepwalking and doing things while asleep can happen

Interactions

  • alcohol — do not drink
  • drowsy antihistamines and other sedating medicines
  • medicines for depression, anxiety, schizophrenia or epilepsy
  • strong painkillers such as codeine, morphine or methadone
  • ciprofloxacin and antifungals such as ketoconazole or itraconazole
  • caffeine — stops zolpidem working

Pregnancy: not usually recommended in pregnancy

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/zolpidem (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
ZolpidemTablet10mgMFDA designated importers with Pre Authorization approval before importcontrolled
ZolpidemTablet5mgMFDA designated importers with Pre Authorization approval before importcontrolled
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