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Vigabartin

Anti-seizure medicine for resistant epilepsy and infantile spasms.

Clinical information

Common uses

  • refractory complex partial seizures, add-on from age 2
  • infantile spasms in babies 1 month to 2 years
  • not a first-line agent

Common side effects

  • blurred vision
  • sleepiness and tiredness
  • dizziness and poor coordination
  • tremor
  • weight gain (children)

Cautions

  • can cause permanent, irreversible vision loss — regular eye checks
  • brain MRI changes reported in infants
  • risk of suicidal thoughts
  • taper slowly to avoid withdrawal seizures

Interactions

  • phenytoin (levels fall — dose may need adjusting)

Pregnancy: may harm the baby — registry enrolment advised

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, vigabatrin tablet label, setid 93ba3894-fd97-4432-9f2d-e7050371e91f (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
VigabartinOral Liquid ( Powder)500 mgPOM
VigabartinOral Liquid500 mgPOM
VigabartinTablet500 mgPOM
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