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Verapamil

A calcium channel blocker for high blood pressure, angina and irregular heartbeats.

Clinical information

Common uses

  • high blood pressure
  • preventing angina chest pain
  • irregular heart rhythms
  • preventing cluster headaches (specialist use)

Common side effects

  • constipation
  • feeling or being sick
  • flushing
  • headaches
  • feeling dizzy or tired

Cautions

  • do not eat grapefruit or drink grapefruit juice
  • do not stop suddenly — blood pressure may rise
  • not suitable with some heart problems or very slow heartbeat
  • alcohol increases its effects

Interactions

  • antibiotics such as clarithromycin, erythromycin or rifampicin
  • statins such as simvastatin or atorvastatin
  • digoxin or ivabradine (heart medicines)
  • dabigatran (blood thinner)
  • St John's wort
  • grapefruit — raises verapamil levels

Pregnancy: can be taken, though not commonly used — doctor will review

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/verapamil (accessed 2026-08-16)

Approved brands & formulations4

Brand nameDosage formStrengthImporterCategory
Calaptin 40Tablet ( Film coated )40 mgauthorized medicine importersPOM
IsoptinTablet40mgauthorized medicine importersPOM
VerapamilTablet40mgPOM
VerapamilParenteral ( Injection )2.5mg/mlPOM
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