MedicinehospitalEssential

Varicella Zoster Immunoglobulin

An antibody injection given after chickenpox exposure to reduce illness severity in high-risk people.

Clinical information

Common uses

protection after chickenpox exposure in high-risk people
immunocompromised people, newborns, premature infants and pregnant women

Common side effects

injection site pain
headache
rash
tiredness
chills

Cautions

give as soon as possible, ideally within 96 hours of exposure
blood clot events can occur
not after severe reactions to human immune globulins
made from human plasma — small infection-transmission risk

Interactions

live vaccines (measles, mumps, rubella, chickenpox) — delay about 3 months

Pregnancy: only if clearly needed — has been used in pregnant women

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, varicella zoster immune globulin (VariZIG) label, setid f367f996-aafa-4b8b-8cb4-63a009cd2015 (accessed 2026-08-16)

Approved brands & formulations2

Brand name	Dosage form	Strength	Importer	Category
Varicella Zoster Immunoglobulin	Parenteral ( Injection )	100IU/ml	—	POM
Varicella Zoster Immunoglobulin	Parenteral ( Injection )	125IU/vial	—	hospital