MedicinePOM

Tofacitinib Citrate

A JAK inhibitor tablet for arthritis and ulcerative colitis after TNF blockers fail.

Clinical information

Common uses

rheumatoid arthritis
psoriatic arthritis and ankylosing spondylitis
ulcerative colitis
juvenile arthritis (age 2+)

Common side effects

upper respiratory tract infections
cold-like symptoms
diarrhoea
headache

Cautions

boxed warning: serious infections including tuberculosis — TB test first
higher risk of death, heart attack and stroke in older patients
increased risk of cancers, including lymphoma and lung cancer
blood clots (DVT, pulmonary embolism) have occurred

Interactions

ketoconazole (strong CYP3A4 inhibitors) — dose reduced
fluconazole — dose reduced
rifampicin (avoid — makes it less effective)
azathioprine, ciclosporin, tacrolimus (avoid — added immunosuppression)
live vaccines (avoid)

Pregnancy: insufficient human data; harmful in animal studies — talk to your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, tofacitinib (tofacitinib citrate) tablet label, setid c963c610-52e5-43ab-aac6-3f7e5341b764 (accessed 2026-08-16)

Approved brands & formulations1

Brand name	Dosage form	Strength	Importer	Category
Jitrit-5	Tablet ( Film coated )	5 mg	ADK Pharmaceutical Company Pvt. Ltd	POM