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Tobramycin

An inhaled aminoglycoside antibiotic for Pseudomonas lung infection in cystic fibrosis.

Clinical information

Common uses

  • cystic fibrosis with Pseudomonas aeruginosa (age 6+)

Common side effects

  • increased cough
  • sore throat
  • increased sputum
  • breathlessness
  • voice changes

Cautions

  • can cause ringing in the ears and hearing loss
  • can harm the kidneys
  • can worsen muscle weakness
  • airway tightening (bronchospasm) can occur after inhaling

Interactions

  • avoid other medicines that harm hearing, kidneys or nerves
  • not recommended with furosemide, ethacrynic acid, urea or IV mannitol

Pregnancy: caution — this drug class can harm the baby; inhaled absorption is minimal

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, tobramycin inhalation solution label, setid 5563e8af-c6c9-42a2-974d-7d364a47f00a (accessed 2026-08-16)

Approved brands & formulations12

Brand nameDosage formStrengthImporterCategory
NebraOphthalmic preparations ( Drops )0.3% (USP)/ mlADK Pharmaceutical Company Pvt. LtdPOM
NebraOphthalmic preparations ( Ointment )0.3% ( 5g )authorized medicine importersPOM
Ocusyn Eye DropsOphthalmic preparations ( Drops )3 mgauthorized medicine importersPOM
Tobi PodhalerInhalation Capsule28 mgauthorized medicine importersPOM
TobramycinInhalation Solution (powder)300 mg/4 mlPOM
TobramycinInhalation Solution (powder)300 mg/ 5 mlPOM
TobramycinOphthalmic preparations ( Drops )0.003POM
TobramycinInhalation Capsule28 mgPOM
TobramycinOphthalmic preparations ( Drops )3 mgPOM
TobrexOphthalmic preparations ( Drops )0.003authorized medicine importersPOM
TobrexOphthalmic preparations ( Drops )3mg/ml ( 5ml )ADK Pharmaceutical Company Pvt. LtdPOM
TobrexOphthalmic preparations ( Ointment )3mg ( 3.5g )ADK Pharmaceutical Company Pvt. LtdPOM
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