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Tetracosactide Hexa-Acetate

Injected hormone used to test adrenal gland function.

Clinical information

Common uses

  • screening test for adrenocortical insufficiency
  • adults and children

Common side effects

  • allergic reactions
  • slow or fast heartbeat
  • raised blood pressure
  • swelling of hands and feet
  • rash

Cautions

  • anaphylaxis has been reported
  • other medicines can make test results inaccurate

Interactions

  • glucocorticoids and spironolactone (falsely raise cortisol — stop on test day)
  • oestrogen-containing medicines (stop 4-6 weeks before testing)

Pregnancy: decades of use show no increased risk

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Cortrosyn (cosyntropin) injection label, setid 0c424fac-b114-41f6-aba8-cf710a34c26c (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
Tetracosactide Hexa-AcetateParenteral ( Injection )250 mcg/mlMFDA designated importers with Pre Authorization approval before importhospital
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