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Tenofovir

An antiviral tablet for HIV (with other medicines) and chronic hepatitis B.

Clinical information

Common uses

  • HIV-1 treatment, combined with other antiretrovirals
  • chronic hepatitis B

Common side effects

  • rash
  • diarrhoea
  • nausea
  • headache
  • depression

Cautions

  • hepatitis B can flare badly after stopping (boxed warning)
  • kidney problems possible — monitoring needed
  • bone thinning possible
  • lactic acidosis — rare but serious

Interactions

  • didanosine (levels rise)
  • atazanavir (must be given with ritonavir)
  • some HIV or hepatitis C medicines raise tenofovir levels
  • other kidney-harming drugs

Pregnancy: only if prescribed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Tenofovir Disoproxil Fumarate tablet label (Strides), setid bcd3120b-60f6-41d8-a512-ed4a62c836b4 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
TenofovirTablet300mgrestricted
Tenofovir AlafenamideTablet25mgrestricted
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