MedicinehospitalEssential

Tenecteplase

A clot-dissolving injection for acute ischemic stroke and major heart attacks (STEMI).

Clinical information

Common uses

acute ischemic stroke
ST-elevation heart attack (STEMI)

Common side effects

bleeding

Cautions

increases bleeding risk — patients are monitored
not given with active bleeding or recent brain/spine surgery
allergic reactions can occur during and after the dose
heart rhythm problems can occur — treatment kept available

Pregnancy: emergency use — life-saving treatment is not withheld in pregnancy

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, TNKase (tenecteplase) label, setid e647640d-c395-4b4b-a0be-1162f9c21d84 (accessed 2026-08-16)

Approved brands & formulations3

Brand name	Dosage form	Strength	Importer	Category
Tenecteplase	Parenteral ( Injection )	30 mg	—	hospital
Tenecteplase	Parenteral ( Injection )	40 mg	—	hospital
Tenecteplase	Parenteral ( Injection )	50 mg	—	hospital