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Succinyl Choline

A fast-acting muscle relaxant injection used during anaesthesia and breathing-tube insertion.

Clinical information

Common uses

  • adjunct to general anaesthesia
  • helping insert a breathing tube
  • muscle relaxation during surgery or ventilation

Common side effects

  • slow or fast heart rate
  • low or high blood pressure
  • heart rhythm disturbances

Cautions

  • boxed warning: cardiac arrest in children with undiagnosed muscle disease
  • can trigger malignant hyperthermia
  • dangerous high potassium after burns or major trauma
  • severe allergic reactions can occur

Interactions

  • promazine, oxytocin, quinidine, beta-blockers, lidocaine — enhance its effect
  • lithium and magnesium salts — enhance its effect
  • drugs that reduce plasma cholinesterase activity

Pregnancy: no harm identified over decades of use; commonly used in caesareans

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Anectine (succinylcholine chloride) label, setid 04a4e6f5-6fa1-42e1-a3f9-21fca7786b15 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
Succinyl CholineParenteral ( Injection )50mg/mlMFDA designated importers with Pre Authorization approval before importhospital
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