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Streptomycin

An injectable aminoglycoside antibiotic mainly used as part of tuberculosis treatment.

Clinical information

Common uses

  • tuberculosis (in combination regimens)
  • plague, tularaemia, brucellosis
  • certain other serious bacterial infections

Common side effects

  • dizziness and balance problems
  • nausea and vomiting
  • numbness or tingling of the face
  • rash
  • fever

Cautions

  • boxed warning: irreversible hearing and balance damage can occur
  • doses must be reduced with kidney problems
  • C. difficile diarrhoea can occur
  • cross-allergy with other aminoglycosides

Interactions

  • ethacrynic acid, furosemide, mannitol (diuretics) — worsen ear toxicity
  • other neurotoxic or kidney-toxic drugs, e.g. gentamicin, cyclosporine — avoid
  • anaesthetics and muscle relaxants — risk of breathing paralysis

Pregnancy: avoid — can harm the baby's hearing

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, streptomycin injection label, setid abd1f64e-4283-4370-aae8-3666316aa36e (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
StreptomycinParenteral ( Injection )1 gmMFDA designated importers with Pre Authorization approval before importhospital
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