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Stavudin

An antiretroviral capsule used with other medicines to treat HIV-1 infection.

Clinical information

Common uses

  • HIV-1 infection (in combination therapy)

Common side effects

  • headache
  • diarrhoea
  • nerve pain or numbness (neuropathy)
  • rash
  • nausea and vomiting

Cautions

  • boxed warning: lactic acidosis and severe liver problems, sometimes fatal
  • boxed warning: pancreatitis, especially combined with didanosine
  • peripheral neuropathy can be severe
  • body fat changes (lipoatrophy) may occur

Interactions

  • zidovudine — avoid combining
  • didanosine — raises pancreatitis and lactic acidosis risk
  • doxorubicin — use with caution
  • ribavirin — use with caution
  • hydroxyurea with didanosine — avoid

Pregnancy: only if clearly needed — serious risks reported with didanosine

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, stavudine capsule label, setid 7501de1e-149d-405e-94f6-da4010952adf (accessed 2026-08-16)

Approved brands & formulations5

Brand nameDosage formStrengthImporterCategory
StavudinCapsule15 mgrestricted
StavudinCapsule30 mgrestricted
StavudinOral Liquid5 mg/5mlrestricted
StavudinCapsule20 mgrestricted
StavudinTablet40 mgrestricted
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