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Salmeterol + Fluticasone

A combination inhaler (steroid plus long-acting bronchodilator) for asthma and COPD.

Clinical information

Common uses

  • twice-daily asthma treatment (age 4 and older)
  • maintenance treatment of COPD

Common side effects

  • upper airway infection or inflammation
  • sore throat
  • hoarse voice
  • oral thrush
  • headache

Cautions

  • not for relieving sudden breathing attacks
  • never combine with another LABA-containing inhaler
  • rinse mouth after use to reduce thrush risk
  • raises pneumonia risk in COPD

Interactions

  • strong CYP3A4 inhibitors, e.g. ritonavir, ketoconazole — not recommended
  • MAO inhibitors and tricyclic antidepressants — extreme caution
  • beta-blockers — may cause severe bronchospasm
  • diuretics — low potassium risk

Pregnancy: insufficient human data — talk to your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, fluticasone propionate and salmeterol inhalation powder label, setid 1349a04c-2024-42b9-b81d-a7d995716ade (accessed 2026-08-16)

Approved brands & formulations18

Brand nameDosage formStrengthImporterCategory
Combiwave SF250Oral Inhaler25mcg (BP)+ 250mcg(BP) (120 Metered Doses)ADK Pharmaceutical Company Pvt. LtdPOM
Combiwave SF 50Inhaler25mcg + 50mcg (120 Metered Doses)authorized medicine importersPOM
Salmeterol + FluticasoneInhaler25mcg/puff + 25 mcg/puff—POM
Salmeterol + FluticasoneInhaler25mcg/puff +250 mcg/puff—POM
Salmeterol + FluticasoneInhaler25mcg/puff + 50 mcg/puff—POM
Salmeterol + Fluticasone BpInhalation Capsule50 mcg + 100 mcg—POM
Salmeterol + Fluticasone BpInhalation Capsule50 mcg + 250 mcg—POM
Salmeterol + Fluticasone BpInhalation Capsule50 mcg + 500 mcg—POM
Salmeterol + Fluticasone PropionateAccuhaler50mcg + 100mcg /puff—POM
Seretide Accuhaler / DiskusAccuhaler50mcg + 500mcg / inhalation 60 inhalationsADK Pharmaceutical Company Pvt. Ltd. and State Trading Organization PlcPOM
Seretide Accuhaler / DiskusAccuhaler50mcg + 250mcg / inhalation 60 inhalationsADK Pharmaceutical Company Pvt. Ltd. and State Trading Organization PlcPOM
Seretide Accuhaler™ / Diskus™ 100Accuhaler50mcg + 100mcg /puffauthorized medicine importersPOM
Seroflo 100Inhalation Capsule50 mcg + 100 mcgauthorized medicine importersPOM
Seroflo-125Inhaler25mcg/puff + 25 mcg/puffauthorized medicine importersPOM
Seroflo 250Inhalation Capsule50 mcg + 250 mcgauthorized medicine importersPOM
Seroflo-250Inhaler25mcg/puff +250 mcg/puffauthorized medicine importersPOM
Seroflo-50Inhaler25mcg/puff + 50 mcg/puffauthorized medicine importersPOM
Seroflo 500Inhalation Capsule50 mcg + 500 mcgauthorized medicine importersPOM
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