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Ropivacaine Hydrochloride

A local anaesthetic injection used for surgery and acute pain relief.

Clinical information

Common uses

  • local or regional anaesthesia for surgery, including caesarean section
  • epidural pain relief after surgery or in labour
  • nerve blocks and local infiltration

Common side effects

  • low blood pressure
  • feeling sick and vomiting
  • slow heartbeat
  • headache
  • back pain

Cautions

  • given only by trained clinicians with resuscitation equipment ready
  • accidental injection into a vein can cause cardiac arrest
  • not for spinal or intravenous regional anaesthesia
  • lower doses for elderly or debilitated patients

Interactions

  • other amide local anaesthetics — additive toxicity
  • fluvoxamine and other strong CYP1A2 inhibitors — raise levels
  • drugs linked to methemoglobinemia, e.g. nitrates, dapsone
  • amiodarone-type heart rhythm drugs — caution

Pregnancy: used in childbirth anaesthesia under specialist supervision

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, ropivacaine hydrochloride (Naropin) label, setid cb6583ff-cde4-4280-aa5b-0bea2b844792 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
Ropivacaine HydrochlorideParenteral ( Injection )7.5mg /mlMFDA designated importers with Pre Authorization approval before importhospital
Ropivacaine HydrochlorideParenteral ( Injection )2mg/mlMFDA designated importers with Pre Authorization approval before importhospital
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