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Repaglinide

A tablet taken before meals to lower blood sugar in type 2 diabetes.

Clinical information

Common uses

  • type 2 diabetes, alongside diet and exercise

Common side effects

  • low blood sugar (hypoglycaemia)
  • upper respiratory infection
  • headache
  • diarrhoea and feeling sick
  • joint and back pain

Cautions

  • skip the dose if you skip a meal
  • not for type 1 diabetes or ketoacidosis
  • not used with NPH insulin — heart risk

Interactions

  • gemfibrozil — must not be combined
  • clopidogrel — avoid; dose limited if unavoidable
  • cyclosporine — dose limited
  • ketoconazole, clarithromycin, trimethoprim — may raise repaglinide levels
  • rifampin, barbiturates, carbamazepine — may reduce its effect
  • beta blockers — may hide low blood sugar warning signs

Pregnancy: no drug-linked risk identified — only if prescribed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, repaglinide label, setid 6ae28683-28cc-408e-90f9-6a3dddfc668d (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
RepaglinideTablet1 mgPOM
RepaglinideTablet0.5 mgPOM
RepaglinideTablet2 mgPOM
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