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Recombinant Growth Hormone

Injected growth hormone for growth failure and hormone deficiency.

Clinical information

Common uses

  • children with growth hormone deficiency and growth failure
  • Prader-Willi and Turner syndromes; born small for age
  • idiopathic short stature
  • adults with growth hormone deficiency

Common side effects

  • injection-site reactions and rashes
  • headaches
  • fluid retention — swelling, joint pain, carpal tunnel (adults)

Cautions

  • not during acute critical illness or active cancer
  • sudden deaths reported in severely obese Prader-Willi children
  • can unmask diabetes — blood sugar monitored
  • can cause raised brain pressure and thyroid or adrenal changes

Interactions

  • glucocorticoids (replacement doses need adjusting)
  • CYP450-metabolised medicines (monitor)
  • oral oestrogen (higher somatropin doses may be needed)
  • insulin and diabetes medicines (doses may need adjusting)

Pregnancy: limited data — discuss with your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Genotropin (somatropin) label, setid ffebf88b-d257-4542-9808-74d9b7167765 (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
Recombinant Growth HormoneParenteral ( Injection )5 mgMFDA designated importers with Pre Authorization approval before importhospital
Recombinant Growth HormoneParenteral ( Injection )6 mgMFDA designated importers with Pre Authorization approval before importhospital
Recombinant Growth HormoneParenteral ( Injection )12 mgMFDA designated importers with Pre Authorization approval before importhospital
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