MedicinePOM

Ranolazine

An extended-release tablet for long-term chest pain (chronic angina).

Clinical information

Common uses

chronic angina

Common side effects

dizziness
headache
constipation
feeling sick

Cautions

can prolong the QT interval (heart rhythm)
not with liver cirrhosis
kidney function monitored if already impaired

Interactions

strong CYP3A inhibitors like ketoconazole or clarithromycin — contraindicated
CYP3A inducers like rifampin or St John's wort — contraindicated
diltiazem, verapamil or erythromycin — dose limited
simvastatin — limit to 20 mg daily
metformin — dose limited
digoxin and tricyclic antidepressants — doses may need reducing

Pregnancy: no human data — only if prescribed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, ranolazine label, setid a624dc7f-921d-4554-a813-f72dca0133c3 (accessed 2026-08-16)

Approved brands & formulations4

Brand name	Dosage form	Strength	Importer	Category
Cartinex	Tablet ( Film coated - ER )	500 mg	ADK Pharmaceutical Company Pvt. Ltd	POM
Cartinex - Od	Tablet ( Film coated - ER )	1000 mg	authorized medicine importers	POM
Ranolazine	Tablet ( Film coated - ER )	1000 mg	—	POM
Ranolazine	Tablet (Extended Release)	500 mg	—	POM