MedicinePOMEssential

Prochlorperazine

An anti-sickness medicine that stops you feeling or being sick.

Clinical information

Common uses

nausea and vomiting, including pregnancy and motion sickness
vertigo and Ménière's disease
sickness from migraines, surgery or other medicines
occasionally anxiety

Common side effects

feeling sleepy or drowsy
blurred vision
dry mouth
headaches
stuffy nose

Cautions

best not to drink alcohol — increases sleepiness
stopping suddenly after long use causes withdrawal symptoms
do not drive if sleepy or heartbeat feels irregular

Interactions

medicines that make you sleepy
medicines that give you a dry mouth
medicines that can affect your heart
other anti-sickness medicines — usually take only one

Pregnancy: can be taken in pregnancy

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/prochlorperazine (accessed 2026-08-16)

Approved brands & formulations4

Brand name	Dosage form	Strength	Importer	Category
Prochlorperazine	Tablet	5 mg	—	POM
Prochlorperazine Maleate	Parenteral ( Injection )	12.5 mg/ml	—	POM
Stemetil	Parenteral ( Injection )	12.5 mg/ml	authorized medicine importers	POM
Stemetil	Tablet	5 mg	authorized medicine importers	POM