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Polidocanol

An injection used to close off small spider and reticular veins in the legs.

Clinical information

Common uses

  • spider veins (up to 1 mm)
  • reticular veins (1 to 3 mm) in the legs

Common side effects

  • mild reactions at the injection site

Cautions

  • not for people with polidocanol allergy or acute blood clot disease
  • anaphylaxis can occur — treatment must be at hand
  • must never be injected into an artery — tissue damage risk

Pregnancy: usually deferred — little benefit during pregnancy; veins often regress after birth

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, polidocanol (Asclera) label, setid bb1f342b-5352-4059-a0b2-e60fd652fd28 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
PolidocanolParenteral ( Injection )0.03MFDA designated importers with Pre Authorization approval before importhospital
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