Medicinehospital

Palonosetron Hydrochloride

Palonosetron is an anti-sickness injection to prevent nausea and vomiting from chemotherapy or surgery.

Clinical information

Common uses

nausea and vomiting from chemotherapy
post-operative nausea and vomiting

Common side effects

headache
constipation

Cautions

allergic reactions including anaphylaxis reported
serotonin syndrome possible with serotonergic medicines

Interactions

serotonergic drugs (e.g. some antidepressants) — serotonin syndrome risk

Pregnancy: no human data — animal studies show no harm

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, palonosetron hydrochloride label, setid 5bfb3984-2b47-4e06-9bbb-d055ebc376c8 (accessed 2026-08-16)

Approved brands & formulations3

Brand name	Dosage form	Strength	Importer	Category
Palonosetron Hydrochloride	Parenteral ( Injection )	0.25mg	MFDA designated importers with Pre Authorization approval before import	hospital
Palonosetron Hydrochloride	Parenteral ( Injection )	300mg/0.5mg	MFDA designated importers with Pre Authorization approval before import	hospital
Palonosetron Hydrochloride Injection	Parenteral ( Injection )	0.05 mg/ml (0.25 mg/5 ml)	State Trading Organization Plc	hospital