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Oxaliplatin

Oxaliplatin is a platinum chemotherapy infusion for colon and colorectal cancer.

Clinical information

Common uses

  • stage III colon cancer after surgery (with fluorouracil/leucovorin)
  • advanced colorectal cancer

Common side effects

  • numbness or tingling in hands and feet
  • low blood cell counts
  • feeling sick and vomiting
  • diarrhoea
  • tiredness

Cautions

  • boxed warning: severe allergic reactions can occur within minutes
  • nerve damage — avoid cold; dose changes may be needed
  • blood counts monitored before each dose
  • can harm an unborn baby — contraception needed

Interactions

  • oral anticoagulants such as warfarin — extra monitoring
  • other QT-prolonging medicines

Pregnancy: can harm an unborn baby — avoid

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, oxaliplatin label, setid 1ac38523-480b-4c0f-97a1-7dfa1432923c (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
OxaliplatinParenteral ( Injection )50mgMFDA designated importers with Pre Authorization approval before importhospital
OxaliplatinParenteral ( Injection )100mgMFDA designated importers with Pre Authorization approval before importhospital
OxaliplatinParenteral ( Injection )200mgMFDA designated importers with Pre Authorization approval before importhospital
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