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Nitroglycerine / Glyceryl Trinitrate

Glyceryl trinitrate (GTN) is a nitrate that treats and prevents angina chest pain, and treats anal fissures.

Clinical information

Common uses

  • relieving angina attacks
  • preventing angina before exercise
  • daily patches to prevent angina
  • rectal ointment for anal fissures

Common side effects

  • headaches (very common)
  • feeling dizzy, weak, tired or sleepy
  • feeling sick
  • flushing (red face)

Cautions

  • never use with erection medicines like sildenafil
  • call 999 if chest pain lasts 10 minutes after 2 doses
  • tablets expire 8 weeks after opening the bottle
  • can make you dizzy or faint — do not drive

Interactions

  • erection medicines (sildenafil, tadalafil, vardenafil) — do not combine
  • blood pressure and heart medicines
  • heparin (anticoagulant)
  • ergotamine-type migraine medicines
  • regular NSAIDs (ibuprofen, aspirin) — may worsen angina
  • alcohol — increases dizziness and fainting

Pregnancy: not harmful in pregnancy — specialist review advised

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/glyceryl-trinitrate-gtn (accessed 2026-08-16)

Approved brands & formulations19

Brand nameDosage formStrengthImporterCategory
AngisedTablet (Sublingual)0.5 mgauthorized medicine importersPOM
AngisedTablet (Sublingual)0.5 mgauthorized medicine importersPOM
GTN SprayTopical Preparation ( Spray )0.4mg/doseADK Pharmaceutical Company Pvt. LtdPOM
Nitrocontin™ 2.6Tablet ( Uncoated Tablet )2.6mgAzmi Naeem Medical & Diagnostic Centre Pvt LtdPOM
Nitrocontin™ 6.4Tablet ( Uncoated Tablet )6.4mgAzmi Naeem Medical & Diagnostic Centre Pvt LtdPOM
Nitroderm TtsTransdermal system10 mg/patchauthorized medicine importersPOM
Nitroderm TtsTransdermal system10 mg/patchauthorized medicine importersPOM
Nitroderm TtsTransdermal system5 mgauthorized medicine importersPOM
Nitroglycerine / Glyceryl TrinitrateOintment0.002POM
Nitroglycerine / Glyceryl TrinitrateParenteral ( Injection )5 mg/mlPOM
Nitroglycerine/ Glyceryl TrinitrateTransdermal system5 mgPOM
Nitroglycerine/ Glyceryl TrinitrateParenteral ( Injection )25 mg/5 mlPOM
Nitroglycerine/ Glyceryl TrinitrateCapsule2.5mgPOM
Nitroglycerine/ Glyceryl TrinitrateCapsule0.8 mgPOM
Nitroglycerine/ Glyceryl TrinitrateTablet (Sublingual)0.5 mgPOM
Nitroglycerine/ Glyceryl TrinitratePatch0.5 mgPOM
Nitroglycerine/ Glyceryl TrinitrateParenteral ( Injection )50 mg/5 mlPOM
Nitroglycerine/ Glyceryl TrinitrateTransdermal system10 mg/patchPOM
NitroplusParenteral ( Injection )25 mg/5 mlauthorized medicine importersPOM
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