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Nintedanib

Nintedanib is a capsule for idiopathic pulmonary fibrosis and other progressive fibrosing lung diseases.

Clinical information

Common uses

  • idiopathic pulmonary fibrosis (IPF)
  • progressive chronic fibrosing interstitial lung diseases

Common side effects

  • diarrhoea
  • feeling sick
  • stomach pain
  • vomiting
  • decreased appetite

Cautions

  • can cause liver injury — regular liver blood tests needed
  • can harm an unborn baby — use effective contraception
  • risk of bleeding and gut perforation
  • not recommended with moderate or severe liver problems

Interactions

  • P-gp and CYP3A4 inhibitors — may raise nintedanib levels
  • smoking lowers nintedanib levels

Pregnancy: can harm an unborn baby — avoid

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, nintedanib label, setid 9925b305-c1fb-43b6-a5fd-e03f14f28e6c (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
NintedanibCapsule150mgPOM
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