MedicinePOM

Neomycin Sulphate

Oral aminoglycoside antibiotic for gut bacteria.

Clinical information

Common uses

infections caused by susceptible bacteria (oral tablets)

Common side effects

nausea
vomiting
diarrhoea
malabsorption with prolonged use

Cautions

can permanently damage hearing and kidneys, even at recommended doses
hearing loss can appear after stopping the drug
not with intestinal obstruction or ulcerative bowel disease
can cause muscle paralysis with anaesthetics

Interactions

other kidney- or ear-toxic drugs (added toxicity)
muscle relaxants and anaesthetics (paralysis risk)
penicillin V, vitamin B12, methotrexate, digoxin (absorption reduced)
warfarin-type anticoagulants (effect enhanced)

Pregnancy: avoid — aminoglycosides can harm the baby's hearing

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, neomycin sulfate tablet label, setid 461f62b9-b9ec-43f2-aee7-0895638105b8 (accessed 2026-08-16)

Approved brands & formulations2

Brand name	Dosage form	Strength	Importer	Category
Hovid Neomycin Cream 0.5% (Hovid)	Topical Preparations ( Cream )	0.5% w/w	Heart Land Pharmacy	POM
Rexom Neomycin	Topical Preparations ( Cream )	0.5% W/W	ADK Pharmaceutical Company Pvt. Ltd	POM