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Mifepristone

A medicine used with misoprostol to end an early pregnancy (up to 70 days).

Clinical information

Common uses

  • medical termination of early pregnancy, taken with misoprostol

Common side effects

  • feeling sick
  • weakness
  • fever or chills
  • vomiting
  • headache

Cautions

  • rare but serious infection or heavy bleeding — seek urgent help (boxed warning)
  • not for suspected ectopic pregnancy
  • not with chronic adrenal failure or long-term steroid treatment
  • not with bleeding disorders, blood thinners or an IUD in place

Interactions

  • CYP3A4 inducers (lower its levels)
  • CYP3A4 inhibitors (raise its levels)
  • medicines with a narrow safety margin (their levels may rise)

Pregnancy: ends pregnancy — birth defects reported if pregnancy continues after failure

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, mifepristone label, setid b63fad9b-7f12-4400-9019-b0586054e534 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
MifepristoneTablet200mgMFDA designated importers with Pre Authorization approval before importhospital
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