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Midazolam

A sedative given by injection before or during surgery and medical procedures.

Clinical information

Common uses

  • sedation before or during medical procedures
  • starting general anaesthesia
  • sedation of ventilated patients in intensive care

Common side effects

  • slowed or paused breathing
  • hiccups
  • nausea or vomiting
  • pain or tenderness at the injection site
  • headache

Cautions

  • can stop breathing — only used with monitoring and resuscitation equipment (boxed warning)
  • with opioids can cause profound sedation, coma and death
  • not for people with acute narrow-angle glaucoma
  • doses must be individualised and injected slowly

Interactions

  • opioids (dangerous breathing depression)
  • erythromycin (prolongs sedation)
  • diltiazem or verapamil (prolong sedation)
  • ketoconazole or itraconazole (antifungals)
  • cimetidine
  • saquinavir (HIV medicine)

Pregnancy: late use can sedate the newborn and cause withdrawal

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, midazolam injection label, setid 1abda8b8-48a8-4995-af86-39220d1aa240 (accessed 2026-08-16)

Approved brands & formulations11

Brand nameDosage formStrengthImporterCategory
Domi InjectionParenteral ( Injection- Intravenous )5mg / 1mlState Trading Organization Plccontrolled
DOMI INJECTION 5MG (1ML AMP)Parenteral ( Injection )5mg/mlcontrolled
MezolamTablet5 mgauthorized medicine importerscontrolled
MezolamParenteral ( Injection- Solution )5 mg / mlState Trading Organization Plccontrolled
MEZOLAMParenteral ( Injection )5mg/mlcontrolled
MidazolamOral Liquid2mg/mlMFDA designated importers with Pre Authorization approval before importcontrolled
MidazolamParenteral ( Injection )5mg/mlMFDA designated importers with Pre Authorization approval before importcontrolled
MidazolamParenteral ( Injection )1 mg/mLMFDA designated importers with Pre Authorization approval before importcontrolled
MidazolamNasal spray5 mg/0.1 mLMFDA designated importers with Pre Authorization approval before importcontrolled
MidazolamTablet7.5mgMFDA designated importers with Pre Authorization approval before importcontrolled
MidazolamTablet5 mgMFDA designated importers with Pre Authorization approval before importcontrolled
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