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Mesalamine

An aminosalicylate (delayed-release tablet) for ulcerative colitis.

Clinical information

Common uses

  • inducing and maintaining remission of ulcerative colitis
  • ulcerative colitis in children 24 kg and over

Common side effects

  • headache
  • wind (flatulence)
  • abnormal liver tests
  • abdominal pain
  • diarrhoea

Cautions

  • kidney function checked before and during treatment
  • acute intolerance syndrome can mimic a colitis flare
  • not with salicylate or aminosalicylate allergy
  • sun sensitivity — protect skin outdoors

Interactions

  • NSAIDs and other kidney-harming drugs
  • azathioprine or 6-mercaptopurine — blood disorder risk

Pregnancy: no clear link to birth defects in studies

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, mesalamine delayed-release tablet label, setid 14ac4435-903b-41f5-a3c4-8c73de3e4cef (accessed 2026-08-16)

Approved brands & formulations6

Brand nameDosage formStrengthImporterCategory
MesalamineCapsule (Delayed Release)1.2 gPOM
MesalamineCapsule (Delayed Release)800 mgPOM
MesalamineTablet250 mgPOM
MesalamineCapsule (Delayed Release)400 mgPOM
MesalamineTablet500 mgPOM
MesalamineTablet375 mgPOM
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