MedicinePOM

Mebeverine Hydrochloride

A muscle relaxant (Colofac) that eases stomach cramps and spasms, including in IBS.

Clinical information

Common uses

stomach cramps, spasms and pain
irritable bowel syndrome (IBS)

Common side effects

skin rash
itchy or red skin

Cautions

not with paralytic ileus (a gut muscle condition)
check first if you have liver or kidney problems
some products contain sucrose

Pregnancy: may be taken if benefits outweigh risks

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/mebeverine (accessed 2026-08-16)

Approved brands & formulations3

Brand name	Dosage form	Strength	Importer	Category
Mebeverine	Tablet	135 mg (BP)	—	POM
Mevir-135	Tablet ( Film coated )	135 mg	authorized medicine importers	POM
Rostil	Tablet ( Film coated )	135 mg	authorized importers after registration of the product	POM