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Losartan Potassium + Hydrochlorothiazide

A combination tablet of losartan (ARB) and hydrochlorothiazide (diuretic) for high blood pressure.

Clinical information

Common uses

  • high blood pressure
  • reducing stroke risk in hypertension with left ventricular hypertrophy

Common side effects

  • dizziness
  • upper respiratory infection
  • cough
  • back pain

Cautions

  • boxed warning: can injure or kill an unborn baby
  • low blood pressure if dehydrated or salt-depleted
  • kidney function and potassium need monitoring
  • can trigger acute glaucoma or worsen lupus

Interactions

  • potassium-raising drugs — high potassium risk
  • lithium — toxicity risk
  • NSAIDs — kidney harm, weaker effect
  • aliskiren in diabetes — do not combine
  • diabetes medicines may need dose changes
  • cholestyramine and colestipol reduce absorption

Pregnancy: do not use — stop as soon as pregnancy is detected

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, losartan potassium and hydrochlorothiazide label, setid 446e6998-01f6-4de0-be57-7fecf5448e95 (accessed 2026-08-16)

Approved brands & formulations5

Brand nameDosage formStrengthImporterCategory
Angizaar-HTablet ( Film coated )50mg (USP) +12.5mg (USP)ADK Pharmaceutical Company Pvt. LtdPOM
Osartil 50 PlusTablet ( Film coated )50 mg (USP) + 12.5 mg (BP)Dial Trade & Travels Pvt LtdPOM
Resilo HTablet ( Film coated )100mg+ 25mgauthorized medicine importersPOM
Resilo HTablet ( Film coated )50mg +12.5mgState Trading Organization PLCPOM
Vazortan- HTablet ( Film coated )50 mg (USP)+12.5 mg (USP)ADK Pharmaceutical Company Pvt. Ltd. And State Trading Organization PlcPOM
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