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Iohexol

An iodine-based contrast agent used for X-ray and CT imaging procedures.

Clinical information

Common uses

  • imaging of blood vessels, spine, joints and body cavities
  • oral or rectal imaging of the digestive tract

Common side effects

  • headache
  • pain, including back pain
  • feeling or being sick
  • dizziness
  • blurred vision or taste changes

Cautions

  • wrong-strength spinal injection can be fatal
  • severe allergic reactions can occur
  • can cause acute kidney injury — keep well hydrated
  • heart complications can occur during or after injection

Interactions

  • metformin (stop around the scan — lactic acidosis risk)
  • radioactive iodine tests or treatment (avoid for 6 weeks)

Pregnancy: not for womb (hysterosalpingography) imaging in pregnancy; otherwise limited data

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, iohexol injection label, setid ff9456ef-c45a-450d-9004-a684af2bcc59 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
OmnipaqueParenteral ( Injection )350 mgI/ml(100ml)hospital
Optiscan 350Parenteral ( Injection- Intravenous )755.0mg/ml(100ml) USPhospital
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