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Hydroxocobalamin

An injectable form of vitamin B12 used to treat and prevent B12 deficiency anaemia.

Clinical information

Common uses

  • vitamin B12 deficiency anaemia, including pernicious anaemia

Common side effects

  • pain, swelling or itching where you had the injection
  • feeling or being sick
  • diarrhoea
  • headaches
  • dizziness or hot flushes

Cautions

  • tell your doctor if you have low potassium or an irregular heartbeat
  • can cause reactions in people allergic to cobalt
  • serious allergic reaction (anaphylaxis) is rare but possible

Interactions

  • usually safe with other medicines, including painkillers
  • contraceptive pills may lower its blood levels, without affecting treatment

Pregnancy: can be used during pregnancy

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/hydroxocobalamin (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
HydroxocobalaminParenteral ( Injection- Solution )1000mg/mlMFDA designated importers with Pre Authorization approval before importhospital
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