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Hydroquinone + Oxybenzone + Octinoxate

A skin-lightening lotion with sunscreen for gradual bleaching of dark skin patches.

Clinical information

Common uses

  • gradual bleaching of dark patches such as melasma, freckles, age spots

Common side effects

  • occasional localised contact dermatitis

Cautions

  • test on a small patch of skin before first use
  • avoid eyes, nose, mouth and lips
  • contains a sulfite that can trigger allergic or asthmatic reactions
  • sunscreen use is essential during treatment

Pregnancy: only if clearly needed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Obagi Nu-Derm Sunfader (hydroquinone, octinoxate, oxybenzone) label, setid e5c450af-958e-41e3-9c2f-fda76b3596f5 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
Hydroquinone Usp + Oxybenzone Usp + Octinoxate UspTopical Preparations ( Cream )2% w/w + 2.5% w/w + 9.0 w/w (30g tube)POM
Melalite 15Topical Preparations ( Cream )2% w/w (USP) + 2.5% w/w (USP) + 9.0 w/w(USP) (30g tube)authorized medicine importersPOM
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