MedicinePOM

Fondaparinux Sodium

An anticoagulant injection that prevents and treats blood clots, mainly around surgery.

Clinical information

Common uses

prevent deep vein thrombosis after hip, knee or abdominal surgery
treat deep vein thrombosis (with warfarin)
treat acute pulmonary embolism (with warfarin)

Common side effects

bleeding complications
anaemia
injection site bleeding, rash or itching
trouble sleeping
low potassium

Cautions

boxed warning: spinal or epidural bleeds with spinal procedures — paralysis risk
not for severe kidney impairment, active major bleeding or body weight under 50 kg
blood counts, kidney tests and stool blood tests monitored
needle guard contains dry natural rubber — latex allergy caution

Interactions

other drugs that raise bleeding risk (NSAIDs, platelet inhibitors, anticoagulants) — stop unless essential

Pregnancy: no clear harm reported — used with close monitoring

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Fondaparinux sodium injection label, setid dffbf7c9-495e-4a33-ac76-57b52f014fc2 (accessed 2026-08-16)

Approved brands & formulations3

Brand name	Dosage form	Strength	Importer	Category
Arixtra	Parenteral ( Injection )	2.5mg /0.5 ml	authorized medicine importers	POM
Fondaparinux Sodium	Parenteral ( Injection )	5 mg/0.4ml	—	POM
Fondaparinux Sodium	Parenteral ( Injection )	2.5mg /0.5 ml	—	POM