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Flupirtine

Non-opioid painkiller for short-term acute pain.

Clinical information

Common uses

  • acute pain for up to 2 weeks
  • adults who cannot use NSAIDs or weak opioids

Cautions

  • withdrawn in the EU (2018) — serious liver injury
  • liver problems kept occurring despite restrictions and weekly liver tests
  • alternative painkillers should be used

Reference information, not medical advice — always follow your doctor or pharmacist. Source: EMA, ema.europa.eu, flupirtine-containing medicinal products referral — withdrawn (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
FlupirtineCapsule100MGPOM
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