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Febuxostat

A tablet that lowers uric acid to manage gout when allopurinol is unsuitable.

Clinical information

Common uses

  • chronic gout when allopurinol fails or cannot be used

Common side effects

  • liver test abnormalities
  • nausea
  • joint pain
  • rash

Cautions

  • higher rate of heart-related death than allopurinol in heart disease
  • gout flares often increase when starting — preventive treatment may help
  • liver failure reported — stop if liver injury develops
  • serious skin reactions possible

Interactions

  • azathioprine (do not combine)
  • mercaptopurine (do not combine)

Pregnancy: data limited — talk to your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, febuxostat label, setid f2c338dc-5bab-49f4-a4ac-d8dea8afeea5 (accessed 2026-08-16)

Approved brands & formulations5

Brand nameDosage formStrengthImporterCategory
FebuxostatTablet40 mgPOM
FebuxostatTablet80 mgPOM
Feluric® 40mgTablet ( Film coated )40mgState Trading Organization PlcPOM
Xanurix-40Tablet ( Film coated )40mgADK Pharmaceutical Company Pvt. LtdPOM
Xanurix-80Tablet ( Film coated )80mgADK Pharmaceutical Company Pvt. LtdPOM
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