MedicinePOM

Evolocumab

An injectable PCSK9 inhibitor that lowers LDL cholesterol and heart risk.

Clinical information

Common uses

reducing heart attack and stroke risk
lowering LDL cholesterol in hypercholesterolaemia
familial hypercholesterolaemia in adults and children 10+

Common side effects

cold-like symptoms
upper respiratory infections
flu
back pain
injection site reactions

Cautions

serious allergic reactions including angioedema — stop if they occur

Pregnancy: data limited — antibody crosses the placenta; talk to your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Repatha (evolocumab) label, setid cd61e902-166d-4aa6-9f3c-a18c1008d07e (accessed 2026-08-16)

Approved brands & formulations1

Brand name	Dosage form	Strength	Importer	Category
Evolocumab	Parenteral ( Injection )	140mg/ml	—	POM