Explore
MedicinehospitalEssential

Etonogestrel

A hormonal contraceptive implant placed under the skin of the arm to prevent pregnancy for up to 5 years.

Clinical information

Common uses

  • long-acting contraception, up to 5 years

Common side effects

  • changes in menstrual bleeding pattern
  • headache
  • weight gain
  • acne
  • breast pain or stomach pain

Cautions

  • must be inserted and removed by a trained professional (boxed warning)
  • removed if a blood clot, jaundice or uncontrolled high blood pressure develops
  • not for people with breast cancer, liver disease or a history of blood clots
  • watch for ectopic pregnancy if pregnancy occurs

Interactions

  • enzyme-inducing medicines and herbal products (CYP3A4 inducers) — may reduce effectiveness

Pregnancy: not for use in pregnancy — implant removed if pregnancy continues

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, NEXPLANON (etonogestrel implant) label, setid 487f8a62-e142-457c-97cc-2e398fde7594 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
EtonogestrelImplant68 mgMFDA designated importers with Pre Authorization approval before importhospital
Implanon NXTImplant68mgauthorized medicine importershospital
Old search API