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Ethinyl Estradiol + Drospirenone

Combined oral contraceptive pill (drospirenone with ethinyl estradiol) to prevent pregnancy.

Clinical information

Common uses

  • prevention of pregnancy

Common side effects

  • premenstrual syndrome
  • headache or migraine
  • breast tenderness
  • nausea or vomiting
  • mood changes

Cautions

  • do not use if over 35 and a smoker — serious cardiovascular risk
  • may carry higher blood clot risk than some other pills
  • can raise potassium — not with kidney or adrenal problems
  • not with breast cancer, liver disease or uncontrolled high blood pressure

Interactions

  • enzyme-inducing drugs reduce effectiveness (use backup contraception)
  • hepatitis C combo ombitasvir/paritaprevir/ritonavir (do not use)
  • long-term potassium-raising medicines (potassium checked)

Pregnancy: do not use — stop if pregnancy occurs

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, drospirenone and ethinyl estradiol label, setid 57d1d945-9fc9-4e79-e063-6294a90a738a (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
Ethinyl Estradiol + DrospirenoneTablet0.03mg + 3mgPOM
Yasmin ®Tablet ( Film coated )0.030mg ( IP ) + 3mg ( IP )State Trading Organization PlcPOM
YazTablet ( Film coated )0.02 mg ( IP )+ 3.0 mg ( IP )State Trading Organization PlcPOM
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