Medicinehospital

Etanercept

Injectable TNF-blocker for rheumatoid arthritis, psoriasis and related conditions.

Clinical information

Common uses

rheumatoid and psoriatic arthritis
ankylosing spondylitis
plaque psoriasis
juvenile idiopathic and psoriatic arthritis

Common side effects

infections
injection site reactions

Cautions

raises risk of serious infections including tuberculosis — TB test first
lymphoma and other cancers reported, some in children
can worsen heart failure or nerve (demyelinating) disease
not started during an active infection

Interactions

live vaccines (avoid)
anakinra (serious infection risk)
abatacept (serious adverse events)
cyclophosphamide (not recommended)

Pregnancy: no clear link to birth defects — discuss with your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Enbrel (etanercept) label, setid a002b40c-097d-47a5-957f-7a7b1807af7f (accessed 2026-08-16)

Approved brands & formulations2

Brand name	Dosage form	Strength	Importer	Category
Etanercept	Parenteral ( Injection )	25 mg/ml	MFDA designated importers with Pre Authorization approval before import	hospital
Etanercept	Parenteral ( Injection )	50 mg/ml	MFDA designated importers with Pre Authorization approval before import	hospital