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Ephedrine Hydrochloride

Injection used to raise dangerously low blood pressure during anaesthesia.

Clinical information

Common uses

  • low blood pressure during anaesthesia

Common side effects

  • nausea
  • vomiting
  • fast heartbeat

Cautions

  • blood pressure monitored closely with interacting drugs
  • repeated doses can stop working (tolerance)

Interactions

  • oxytocin-type drugs (dangerous blood pressure rise)
  • MAOI antidepressants, clonidine, atropine (stronger effect)
  • beta blockers and alpha blockers (weaker effect)
  • digoxin-type heart drugs (rhythm problems)
  • guanethidine (blood pressure drug stops working)
  • theophylline (more nausea, nervousness, insomnia)

Pregnancy: no known risk of birth defects from available data

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, ephedrine sulfate injection label, setid d89dd8d5-7698-61db-e053-2a95a90a764b (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
EDELINEParenteral ( Injection )30mg/mlState Trading Organization Plccontrolled
EFIPRESParenteral ( Injection )30mg/mlcontrolled
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