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Doxapram Hcl

Doxapram is an injectable breathing stimulant used after anaesthesia or drug overdose.

Clinical information

Common uses

  • stimulating breathing after anaesthesia
  • drug-induced breathing and CNS depression
  • short-term aid in acute breathing failure in COPD

Common side effects

  • flushing and sweating
  • dizziness and headache
  • cough and rapid breathing
  • nausea, vomiting or diarrhoea
  • mild to moderate rise in blood pressure

Cautions

  • not for people with epilepsy or seizure disorders
  • not with mechanical ventilation, pulmonary embolism or airway obstruction
  • not with head injury, stroke or severe heart disease
  • contains benzyl alcohol — toxicity risk in newborns

Interactions

  • volatile anaesthetics (delay doxapram — heart rhythm risk)

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, doxapram hydrochloride injection label, setid 954859c0-a121-34d6-e053-2a95a90a1e19 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
Doxapram HclParenteral ( Injection )20mg/mlMFDA designated importers with Pre Authorization approval before importhospital
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