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Digoxin

Heart medicine (cardiac glycoside) that steadies and strengthens the heartbeat.

Clinical information

Common uses

  • irregular heartbeats including atrial fibrillation
  • heart failure symptoms, alongside other medicines

Common side effects

  • feeling dizzy
  • feeling or being sick
  • diarrhoea
  • changes in vision
  • skin rashes

Cautions

  • regular blood tests needed for kidneys, potassium, magnesium and calcium
  • more than 2 common side effects may mean too much digoxin
  • do not stop suddenly — condition can worsen
  • thyroid, kidney and bowel problems change how it works

Interactions

  • amiodarone, verapamil or diltiazem (heart medicines)
  • diuretics such as furosemide
  • antibiotics such as clarithromycin, erythromycin or rifampicin
  • NSAIDs such as ibuprofen or diclofenac
  • HIV medicines such as ritonavir
  • St John's wort (herbal remedy)

Pregnancy: can be taken under specialist supervision

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/digoxin (accessed 2026-08-16)

Approved brands & formulations4

Brand nameDosage formStrengthImporterCategory
DigoxinParenteral ( Injection )0.25 mg/mlMFDA designated importers with Pre Authorization approval before importhospital
DigoxinTablet250mcgPOM
DigoxinTablet62.5mcgPOM
DigoxinOral liquid ( Syrup )50mcgPOM
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