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Diazepam

Benzodiazepine used to treat anxiety, seizures and muscle spasms.

Clinical information

Common uses

  • severe anxiety
  • seizures (fits)
  • muscle spasms
  • sedation before treatment or surgery

Common side effects

  • feeling less alert
  • feeling drowsy
  • tiredness
  • increased anxiety and depression
  • low blood pressure

Cautions

  • short-term use only (up to 4 weeks) — risk of addiction
  • do not stop suddenly — withdrawal symptoms
  • can make you sleepy — do not drive until you feel OK
  • may not suit kidney, liver, heart or breathing problems

Interactions

  • antidepressants such as fluvoxamine and fluoxetine
  • antipsychotics such as clozapine
  • antihistamines that make you sleepy
  • general anaesthetics
  • alcohol and grapefruit juice — avoid
  • caffeine — can reduce diazepam's effect

Pregnancy: avoid — only if a doctor advises it

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/diazepam (accessed 2026-08-16)

Approved brands & formulations13

Brand nameDosage formStrengthImporterCategory
DIAPOTablet5mgcontrolled
DiazepamRectal Solution10 mg/tubeMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamTablet2mgMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamParenteral ( Injection )5 mg/mLMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamParenteral ( Injection )10mg/2mlMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamRectal solution2.5mgMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamRectal solution5mgMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamTablet10mgMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamTablet1mgMFDA designated importers with Pre Authorization approval before importcontrolled
DiazepamTablet5mgMFDA designated importers with Pre Authorization approval before importcontrolled
Diazepam Oral LiquidOral Liquid2mg/5mlMFDA designated importers with Pre Authorization approval before importcontrolled
Diazepam Rectal GelRectal Gel2 mg/5mlMFDA designated importers with Pre Authorization approval before importcontrolled
LoriParenteral ( Injection )10mg/2mlcontrolled
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