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Dextran + Sodium Chloride

Intravenous dextran 40 in sodium chloride, used for shock and clot prevention.

Clinical information

Common uses

  • adjunctive treatment of shock from bleeding, burns or surgery
  • priming fluid in heart-lung machines
  • preventing vein clots after high-risk surgery

Common side effects

  • mild hives
  • fever reactions
  • irritation or clots at the infusion site

Cautions

  • rare severe allergic-type reactions — watch closely at start of infusion
  • sodium-containing solutions need great care in heart failure
  • can overload the circulation causing fluid buildup
  • high doses can increase bleeding tendency

Interactions

  • heparin or warfarin (blood thinners) — not with clotting defects they cause

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, LMD in Sodium Chloride (dextran 40) label, setid 3c273512-84e2-2cea-b201-12345a6bd1fe (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
Dextran Bp + Sodium Chloride IpParenteral ( Injection )10.0g + 0.9gMFDA designated importers with Pre Authorization approval before importhospital
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