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Dextran

Intravenous fluid (dextran 40) used to treat shock and prevent blood clots after surgery.

Clinical information

Common uses

  • adjunctive treatment of shock from bleeding, burns or surgery
  • priming fluid in heart-lung machines
  • preventing vein clots after high-risk surgery

Common side effects

  • mild hives
  • fever reactions
  • irritation or clots at the infusion site

Cautions

  • rare severe allergic-type reactions — watch closely at start of infusion
  • can overload the circulation causing fluid buildup
  • high doses can increase bleeding tendency
  • avoid exceeding doses in advanced kidney disease

Interactions

  • heparin or warfarin (blood thinners) — not with clotting defects they cause

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, LMD (dextran 40) label, setid 3c273512-84e2-2cea-b201-12345a6bd1fe (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
DextranParenteral ( Injection )0.7MFDA designated importers with Pre Authorization approval before importhospital
DextranParenteral ( Injection )40MFDA designated importers with Pre Authorization approval before importhospital
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