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Deferasirox

Iron chelator taken by mouth to remove excess iron caused by repeated blood transfusions.

Clinical information

Common uses

  • chronic iron overload from blood transfusions
  • iron overload in non-transfusion-dependent thalassaemia

Common side effects

  • diarrhoea
  • vomiting
  • feeling sick
  • stomach pain
  • skin rash

Cautions

  • can cause kidney failure, liver failure and gut bleeding — sometimes fatal
  • needs regular kidney and liver blood tests
  • not for people with poor kidney function or low platelets
  • can suppress bone marrow — monitor blood counts

Interactions

  • aluminium-containing antacids — do not take together
  • repaglinide (diabetes medicine) — levels increased
  • theophylline — avoid, levels may rise
  • busulfan — levels increased, needs monitoring

Pregnancy: only if benefits outweigh risks

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, deferasirox label, setid 2c2842a0-7781-4047-84cd-88bd018e10c7 (accessed 2026-08-16)

Approved brands & formulations10

Brand nameDosage formStrengthImporterCategory
Asunra 400mgTablet ( Dispersible )400mgState Trading Organization PlcPOM
DeferasiroxTablet125mg—POM
DeferasiroxTablet500mg—POM
DeferasiroxTablet250mg—POM
Jadenu 180mgTablet ( Film coated )180 mgState Trading Organization PlcPOM
Jadenu 180mgTablet ( Film coated )180mgState Trading Organization PlcPOM
Jadenu 360Tablet ( Film coated )360mgState Trading Organization PlcPOM
Jadenu 360mgTablet ( Film coated )360mgState Trading Organization PlcPOM
Jadenu 90Tablet ( Film coated )90mgState Trading Organization PlcPOM
Jadenu 90Tablet ( Film coated )90mgState Trading Organization PlcPOM
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