MedicinePOM

Dapagliflozin + metformin hydrochloride

A combination tablet of dapagliflozin and metformin for type 2 diabetes.

Clinical information

Common uses

type 2 diabetes (with diet and exercise)
reducing heart failure and kidney disease risks

Common side effects

genital fungal infections (women)
cold-like symptoms (nasopharyngitis)
urinary tract infection
diarrhoea and nausea
headache

Cautions

lactic acidosis — rare but can be fatal (boxed warning)
not with severe kidney disease
stop if ketoacidosis is suspected
serious genital infections, including rare Fournier's gangrene

Interactions

topiramate and other carbonic anhydrase inhibitors
cimetidine, ranolazine, dolutegravir (raise metformin levels)
excessive alcohol (lactic acidosis risk)
insulin or sulfonylureas (low blood sugar risk)
lithium (levels may fall)

Pregnancy: not recommended in the second and third trimesters

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, Xigduo XR (dapagliflozin/metformin HCl) label, setid ac8a0f7b-9f69-4495-abbc-3a47cd75a859 (accessed 2026-08-16)

Approved brands & formulations4

Brand name	Dosage form	Strength	Importer	Category
XIGA Met	Tablet ( Film coated )	5 mg + 1000 mg	ADK Pharmaceutical Company Pvt. Ltd	POM
Xigduo XR	Tablet (Extended Release)	10mg + 1000mg	State Trading Organization Plc	POM
Xigduo XR	Tablet (Extended Release)	5mg + 1000mg	State Trading Organization Plc	POM
Zucapride- M 10 Forte	Tablet ( Film coated )	10 mg + 1000 mg ( USP )	ADK Pharmaceutical Company Pvt. Ltd	POM