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Dantrolene Sodium

A muscle relaxant capsule used for long-term muscle spasticity.

Clinical information

Common uses

  • chronic spasticity

Common side effects

  • drowsiness
  • dizziness
  • weakness
  • general tiredness (malaise, fatigue)
  • diarrhoea, which may be severe

Cautions

  • can cause fatal liver damage — liver tests needed
  • not with active liver disease (hepatitis, cirrhosis)
  • extra care in women and people over 35
  • stop if hepatitis symptoms or jaundice appear

Interactions

  • sedatives and tranquillisers (more drowsiness)
  • oestrogen therapy (possible liver toxicity)
  • calcium channel blockers like verapamil — avoid in malignant hyperthermia
  • vecuronium (stronger muscle block)

Pregnancy: only if clearly needed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, dantrolene sodium capsule label, setid 90414d2f-7b2c-47f9-a096-2e7b7dd052de (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
Dantrolene SodiumParenteral ( Injection )20 gMFDA designated importers with Pre Authorization approval before importhospital
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