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Danazol

A hormonal medicine with androgen-like effects, used for conditions like hereditary angioedema.

Clinical information

Common uses

  • hereditary angioedema (long-term protection)

Common side effects

  • weight gain, acne and oily skin
  • unwanted hair growth and voice changes
  • menstrual disturbances or missed periods
  • flushing, sweating and vaginal dryness

Cautions

  • never use in pregnancy — can masculinise a female baby
  • blood clots and life-threatening strokes reported
  • liver damage, including tumours, with long-term use
  • raised pressure in the skull (pseudotumor cerebri)

Interactions

  • warfarin (bleeding time prolonged)
  • carbamazepine (levels rise)
  • diabetes medicines (insulin resistance)
  • ciclosporin and tacrolimus (more kidney toxicity)
  • statins such as simvastatin (muscle damage risk)
  • synthetic vitamin D analogues (high calcium)

Pregnancy: contraindicated — do not use

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, danazol capsule label, setid e19acee5-ff33-45a5-bbbf-801756bc59b4 (accessed 2026-08-16)

Approved brands & formulations4

Brand nameDosage formStrengthImporterCategory
DanazolCapsule100 mgPOM
DanazolCapsule200 mgPOM
DanogenCapsule200 mgauthorized medicine importersPOM
DanogenCapsule100 mgauthorized medicine importersPOM
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