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Cytarabine

A chemotherapy injection used mainly to treat acute leukaemias.

Clinical information

Common uses

  • remission induction in acute non-lymphocytic leukaemia
  • acute lymphocytic leukaemia
  • blast phase of chronic myelocytic leukaemia
  • meningeal leukaemia (given into spinal fluid)

Common side effects

  • loss of appetite
  • nausea and vomiting
  • diarrhoea
  • mouth and anal sores or ulcers
  • fever and rash

Cautions

  • strong bone marrow suppressant — infection and bleeding risk
  • needs close hospital monitoring with daily blood counts
  • cytarabine syndrome: fever, muscle and bone pain, rash

Interactions

  • digoxin (levels may fall — monitor)
  • gentamicin (may work less well against some bacteria)
  • flucytosine (its effect may be inhibited)

Pregnancy: avoid — can harm the baby, especially in the first trimester

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, cytarabine injection label, setid 277597b0-7d85-40a3-a34a-70c6a883fc6d (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
CytarabineParenteral ( Injection )100mg/5mlMFDA designated importers with Pre Authorization approval before importhospital
CytarabineParenteral ( Injection )500mg/5mlMFDA designated importers with Pre Authorization approval before importhospital
CytarabineParenteral ( Injection )100mg/1mlMFDA designated importers with Pre Authorization approval before importhospital
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